Santa Cruz is divided into 18 barangays, namely:
- Astorga
- Bato
- Coronon
- Darong
- Inawayan
- Jose Rizal
- Matutungan
- Melilia
- Saliducon
- Sibulan
- Sinoron
- Tagabuli
- Tibolo
- Tuban
- Zone I (Poblacion)
- Zone II (Poblacion)
- Zone III (Poblacion)
- Zone IV (Poblacion)
OFFICIALS
Mayor
Jaime G. Lao Jr.
Vice-Mayor
Jerome A. Undalok
MUNICIPAL COUNCIL
- Jose Nelson Z. Sala Sr.
- Charlotte F. Gallego
- Anselmo A. Datu
- Nestor B. Crave
- Michelle O. Orpilla
- Apolinar C. Ugdoracion Jr.
- Michel Louise R. Bajo
- Ronald R. Cruda
